Aphidicolin, >99%, MP Biomedicals™

Description

Aphidicolin from Nigrospora oryzae ≥98%, Free Flowing Powder

• It is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.
• Inhibits the early S-phase of the cell cycle. DNA polymerase α and δ reversible inhibitor.
• Potentiates apoptosis induced by arabinosyl nucleosides in leukemia cell lines.
• Also induces apoptosis in HeLa S3 cells, but inhibits vincristine-induced apoptosis in the p53-negative human prostate cancer cell line PC-3.

Specifications

Chemical Identifiers

• CAS: 38966-21-1
• Molecular Formula: C20H34O4
• InChI Key: NOFOAYPPHIUXJR-APNQCZIXSA-N
• PubChem CID: 457964
• ChEBI: CHEBI:2766
• SMILES: CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O

• Color: White
• Quantity: 5 mg
• Synonym: aphidicolin, unii-192tj6pp19, ccris 1783, chembl29711, 3r,4r,4ar,6as,8r,9r,11as,11bs-4,9-bis hydroxymethyl-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta a naphthalene-3,9-diol, 9,15-cyclo-c,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, 3alpha,4alpha,5alpha,17alpha, +-aphidicolin, 8,11a-methano-11ah-cyclohepta a naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, 3r-3-alpha,4-alpha,4a-alpha,6a-beta,8-beta,9-beta,11a-beta,11b-beta, +/--aphidicolin, aphidicolin, +/-
• Molecular Weight (g/mol): 338.488
• Formula Weight: 338.5
• Physical Form: Powder
• Chemical Name or Material: Aphidicolin, For TLC analysis