Atiprimod dihydrochloride, Tocris Bioscience™

Description

JAK2 inhibitor

JAK2 inhibitor (IC50 = 397 nM). Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.

Specifications

• CAS: 130065-61-1
• Molecular Formula: C22H46Cl2N2
• Quantity: 10 mg
• Synonym: atiprimod dihydrochloride, atiprimod dihydrochloride usan, atiprimod hcl, atiprimod hydrochloride, 2-3-diethylamino propyl-8,8-dipropyl-2-azaspiro 4.5 decane dihydrochloride, 2-azaspiro 4.5 decane-2-propanamine n,n-diethyl-8,8-dipropyl-, dihydrochloride, 2-azaspiro 4.5 decane-2-propanamine, n,n-diethyl-8,8-dipropyl-, dihydrochloride, 3-8,8-dipropyl-3-azaspiro 4.5 decan-3-yl-n,n-diethylpropan-1-amine dihydrochloride, n,n-diethyl-8,8-dipropyl-2-azaspiro 4.5 decane-2-propanamine dihydrochloride
• InChI Key: MOUZYBYTICOTFQ-UHFFFAOYSA-N
• SMILES: CCCC1(CCC2(CC1)CCN(C2)CCCN(CC)CC)CCC.Cl.Cl
• IUPAC Name: 3-(8,8-dipropyl-2-azaspiro[4.5]decan-2-yl)-N,N-diethylpropan-1-amine;dihydrochloride
• Molecular Weight (g/mol): 409.524
• PubChem CID: 166556
• Formula Weight: 409.52
• Chemical Name or Material: Atiprimod dihydrochloride