ATP7B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5122223

Product Code. 17713624

Description

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Specifications

• Antigen: ATP7B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Atp7b
• Gene Alias: Atp7a; ATP7B; ATPase copper transporting beta; ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease); copper pump 2; Copper-transporting ATPase 2; Hts; PINA; PINA gene, promoter; pineal night-specific ATPase; PWD; RP11-327P2.1; RP11-327P2.3; toxic milk; tx; WC1; WD; Wilson disease-associated protein; wilson disease-associated protein homolog; Wilson protein; Wnd; WND/140 kDa
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 540
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.76 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P35670
• Gene Symbols: Atp7b
• Immunogen: Thr59-Val426 (Accession P35670), with N-terminal His Tag
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG