ATR Recombinant Polyclonal Antibody (23HCLC), Invitrogen™

Rabbit Recombinant Polyclonal Antibody

Brand:  Invitrogen 710746

Product Code. 15923904

Description

This antibody is predicted to react with Monkey, Cat and Bovine. Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

Specifications

• Antigen: ATR
• Classification: Recombinant Polyclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: Q13535
• Gene Symbols: ATR
• Immunogen: Peptides corresponding to Human ATR (aa 7-26, 442-459)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry
• Clone: 23HCLC
• Conjugate: Unconjugated
• Gene: ATR
• Gene Alias: 2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 545
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid