Azelaic acid, tech. 80%, Thermo Scientific Chemicals

Description

It is applied in organic synthesis, lacquers, polyester adhesives, and urethane elastomers. Azelaic acid directly inhibits kallikrein 5 (KLK5), down regulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and up regulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPAR? is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Notes
Store away from strong oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 123-99-9
• Molecular Formula: C9H16O4
• Molecular Weight (g/mol): 188.223
• MDL Number: MFCD00004432
• InChI Key: BDJRBEYXGGNYIS-UHFFFAOYSA-N
• Synonym: azelaic acid, finacea, anchoic acid, azelex, lepargylic acid, skinoren, 1,7-heptanedicarboxylic acid, heptanedicarboxylic acid, 1,9-nonanedioic acid, emerox 1110
• PubChem CID: 2266
• ChEBI: CHEBI:48131
• IUPAC Name: nonanedioic acid
• SMILES: C(CCCC(=O)O)CCCC(=O)O

• Melting Point: ∼102°C
• Boiling Point: 286°C (100mmHg)
• Beilstein: 1101094
• Merck Index: 14,905
• Solubility Information: Soluble in water at 20°C 2.4g/L. Soluble in ethanol (5%),DMSO,methanol (70mg/ml),and alcohol.
• Formula Weight: 188.22
• Percent Purity: 80%
• Grade: Technical
• Density: 1.225
• Quantity: 2500 g
• Flash Point: 215°C (419°F)
• Chemical Name or Material: Azelaic acid

RUO – Research Use Only