BC 11 hydrobromide, Tocris Bioscience™

Description

Selective urokinase (uPA) inhibitor

Selective urokinase (uPA) inhibitor (IC50 = 8.2 μM). Exhibits no activity at 8 other related enzymes. Inhibits clot lysis with no effect on clot formation. Also decreases viability of MDA-MB231 breast cancer cells in vitro.

Specifications

Chemical Identifiers

• CAS: 443776-49-6
• Molecular Formula: C8H12BBrN2O2S
• Molecular Weight (g/mol): 290.97
• InChI Key: PAFZAMOVHIRQOD-UHFFFAOYSA-N
• Synonym: bc 11 hydrobromide, carbamimidothioic acid 4-boronophenyl methyl ester hydrobromide
• PubChem CID: 78243712
• IUPAC Name: [4-(carbamimidoylsulfanylmethyl)phenyl]boronic acid;hydrobromide
• SMILES: B(C1=CC=C(C=C1)CSC(=N)N)(O)O.Br

• Quantity: 10 mg
• Formula Weight: 290.97
• Percent Purity: >98%
• Chemical Name or Material: BC 11 hydrobromide