beta Amyloid (1-40) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen 44348A

Product Code. 10553185

Description

This antibody reacts with human beta Amyloid (1-40). No significant cross-reactivity to beta Amyloid (1-42) has been observed. Previous lots have shown no cross-reactivity against beta Amyloid (1-43). The antibody has been used in ELISA. Previous lots of this antibody have been used in dot blots, RIA, and other related assays.

Beta-amyloid is a 40–43 amino acid peptide cleaved from amyloid precursor protein, and a putative gamma-secretase. Amyloid beta (1-40) together with Amyloid beta (1-42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the amyloid beta (40) and amyloid beta (42) alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue.

Specifications

• Antigen: beta Amyloid (1-40)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APP
• Gene Alias: A beta 1 40; A β 1 40; A4; AAA; AB40; Abeta; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; Amyloid beta 1 40; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid β; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; App; APP-C57; APP-C59; APP-C99; APPI; appican; Aβ 1 40; B APP40; BAPP40; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; BetaAPP40; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; β APP40; βAPP40; testicular tissue protein Li 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 351
• Content And Storage: -20°C
• Form: Liquid

• Applications: Dot Blot, ELISA, Immunocytochemistry, Radioimmune Assays (RIA)
• Concentration: 1 mg/mL
• Formulation: Dulbecco's PBS with no preservative; pH 7.3
• Gene Accession No.: P05067
• Gene Symbols: APP
• Immunogen: The antibody was produced using a synthetic peptide derived from amino acids 34-40 within the C-terminal region of human beta-Amyloid protein.
• Quantity: 25 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG