beta-Nicotinamide adenine dinucleotide reduced disodium salt trihydrate, 98%, Thermo Scientific Chemicals

Description

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Solubility
It is soluble in water.

Notes
Store with desiccant. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C Light sensitive. Hygroscopic.

Specifications

Chemical Identifiers

• CAS: 497934-76-6
• Molecular Formula: C21H27N7Na2O14P2
• Molecular Weight (g/mol): 709.41
• MDL Number: MFCD00036200
• InChI Key: QRGNQKGQENGQSE-WUEGHLCSSA-L
• Synonym: nadh disodium salt trihydrate, beta-nicotinamide adenine dinucleotide reduced disodium salt trihydrate
• PubChem CID: 101609545
• IUPAC Name: disodium [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl ({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
• SMILES: [Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O

• Color: White to Yellow
• Quantity: 1 g
• Solubility Information: It is soluble in water.
• Formula Weight: 763.46 (709.41 Anhydrous)
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: beta-Nicotinamide adenine dinucleotide reduced disodium salt trihydrate

RUO – Research Use Only