beta-Propiolactone, 97%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11440797	Thermo Scientific Alfa Aesar B23197.03	1 g
11450797	Thermo Scientific Alfa Aesar B23197.06	5 g
11460797	Thermo Scientific Alfa Aesar	25 g

Description

Beta-Propiolactone is widely used as a sterilizing and sporicidal agent, which is used to sterilize blood plasma, vaccines, tissue grafts, surgical instruments and enzymes. It finds an application in the manufacturing of acrylic acid and its esters. It is utilized as an intermediate in the synthesis of synthetic compounds.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Beta-Propiolactone is widely used as a sterilizing and sporicidal agent, which is used to sterilize blood plasma, vaccines, tissue grafts, surgical instruments and enzymes. It finds an application in the manufacturing of acrylic acid and its esters. It is utilized as an intermediate in the synthesis of synthetic compounds.

Solubility
Miscible with water and organic solvents.

Notes
Flammable material. Should be stored in a separate safety storage cabinet or room. Keep away from heat and sources of ignition.

Chemical Identifiers

• CAS: 57-57-8
• Molecular Weight (g/mol): 72.06
• InChI Key: VEZXCJBBBCKRPI-UHFFFAOYSA-N
• PubChem CID: 2365
• IUPAC Name: oxetan-2-one

• Molecular Formula: C3H4O2
• MDL Number: MFCD00005169
• Synonym: beta-propiolactone, propiolactone, 2-oxetanone, propanolide, betaprone, 3-propanolide, 1,3-propiolactone, 3-propiolactone, beta-propionolactone, beta-propiolakton
• ChEBI: CHEBI:49073
• SMILES: O=C1CCO1

Specifications

• CAS: 57-57-8
• Density: 1.146
• Flash Point: 70°C (158°F)
• Molecular Formula: C3H4O2
• MDL Number: MFCD00005169
• Sensitivity: Moisture sensitive
• Synonym: beta-propiolactone, propiolactone, 2-oxetanone, propanolide, betaprone, 3-propanolide, 1,3-propiolactone, 3-propiolactone, beta-propionolactone, beta-propiolakton
• InChI Key: VEZXCJBBBCKRPI-UHFFFAOYSA-N
• IUPAC Name: oxetan-2-one
• PubChem CID: 2365
• Formula Weight: 72.06
• Physical Form: Liquid

• Melting Point: -34°C
• Boiling Point: 161°C to 163°C
• Assay Percent Range: 0.97
• Refractive Index: 1.413
• UN Number: UN3382
• Merck Index: 14,7820
• Solubility Information: Miscible with water and organic solvents.
• SMILES: O=C1CCO1
• Molecular Weight (g/mol): 72.06
• ChEBI: CHEBI:49073
• Percent Purity: 97%
• Chemical Name or Material: beta-Propiolactone

Safety and Handling

GHS H Statement
H330-H350-H227-H315-H319
Fatal if inhaled.
May cause cancer.
Combustible liquid.
Causes skin irritation.
Causes serious eye irritation.

P201-P202-P210-P235-P260-P264b-P271-P280i-P281-P284-P302+P352-P304+P340-P305+P351+P338-P308+P313-P310-P332+P313-P362-P370+P378q-P501c

H227-H315-H319-H330-H350

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC BY INHALATION LIQUID, N.O.S.

missing translation for 'einecsNumber' : 200-340-1

missing translation for 'rtecsNumber' : RQ7350000

missing translation for 'tsca' : Yes

Recommended Storage : Store at -20°C

Product Identifier

• beta-Propiolactone

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 2
• Carcinogenicity Category 1B
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H330-Fatal if inhaled.
• H350-May cause cancer.

Precautionary Statement

• P201-Obtain special instructions before use.
• P202-Do not handle until all safety precautions have been read and understood.
• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash face, hands, and anyexposed skin thoroughly after handling.
• P271-Use only outdoors or in a well-ventilated area.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P284-¢In case of inadequate ventilation! wear respiratory protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.
• P362+P364-Take off contaminated clothing and wash it before reuse.
• P370+P378-In case of fire: Use dry sand, dry chemical, or alcohol-resistant foam to extinguish.
• P403+P233-Store in a well-ventilated place. Keep container tightly closed.
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : .beta.-Propiolactone

RUO – Research Use Only