BIBR 1532, Tocris Bioscience™

Description

Selective telomerase inhibitor

Selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCI-H460 lung carcinoma cells and eventual growth arrest.

Specifications

Chemical Identifiers

• CAS: 321674-73-1
• Molecular Formula: C21H17NO3
• Molecular Weight (g/mol): 331.371
• InChI Key: PGFQXGLPJUCTOI-WYMLVPIESA-N
• Synonym: e-2-3-naphthalen-2-yl but-2-enamido benzoic acid, chembl27323, 2-2e-3-naphthalen-2-yl but-2-enamido benzoic acid, 2-3-naphthalen-2-yl-but-2-enoylamino-benzoic acid, 2-e-3-naphthalen-2-yl-but-2-enoylamino-benzoic acid, 2-2e-3-naphthalen-2-yl but-2-enoyl amino benzoic acid, 2-2e-3-2-naphthalenyl-1-oxo-2-butenyl amino benzoic acid, 2-2e-3-2-naphthalenyl-1-oxo-2-butenyl1-yl amino benzoic acid, 2-2e-3-2-naphthalenyl-1-oxo-2-butenyl1-yl amino benzoicacid
• PubChem CID: 9927531
• IUPAC Name: 2-[[(E)-3-naphthalen-2-ylbut-2-enoyl]amino]benzoic acid
• SMILES: CC(=CC(=O)NC1=CC=CC=C1C(=O)O)C2=CC3=CC=CC=C3C=C2

• Quantity: 10 mg
• Formula Weight: 331.36
• Percent Purity: >98%
• Chemical Name or Material: BIBR 1532