(-)-Bicuculline methiodide, Tocris Bioscience™

Description

GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)

Methiodide form of classical GABAA receptor antagonist (+)-bicuculline . More water-soluble and stable. Non-GABA receptor-mediated actions reported, including actions on calcium-dependent potassium channels.

Methobromide Salt and Methochloride Salt also available.

Specifications

Chemical Identifiers

• CAS: 40709-69-1
• Molecular Formula: C21H20INO6
• Molecular Weight (g/mol): 509.296
• InChI Key: HKJKCPKPSSVUHY-GRTNUQQKSA-M
• Synonym: --bicuculline methiodide, bicuculline methiodide, 1 s ,9 r---bicuculline methiodide, 5s-5-6r-6,8-dihydro-8-oxofuro 3,4-e-1,3-benzodioxol-6-yl-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo 4,5-g isoquinolinium iodide, 1,3-dioxolo 4,5-g isoquinolinium, 5-6r-6,8-dihydro-8-oxofuro 3,4-e-1,3-benzodioxol-6-yl-5,6,7,8-tetrahydro-6,6-dimethyl-, iodide, 5s, 1,3-dioxolo 4,5-g isoquinolinium, 5-6,8-dihydro-8-oxofuro 3,4-e-1,3-benzodioxol-6-yl-5,6,7,8-tetrahydro-6,6-dimethyl-, iodide, r-r*,s*, opera_id_515, --bicucullinemethiodide, 1 s ,9 r---bicuculline methiodide hpce, 5r-5-6s-6,8-dihydro-8-oxofuro 3,4-e-1,3-benzodioxol-6-yl-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo 4,5-g isoquinolinium iodide
• PubChem CID: 104871
• IUPAC Name: (6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one;iodide
• SMILES: C[N+]1(CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3)C.[I-]

• Quantity: 10 mg
• Formula Weight: 509.3
• Percent Purity: >99%
• Chemical Name or Material: (-)-Bicuculline methiodide