Brepocitinib P-Tosylate, MedChemExpress

MedChemExpress Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.

Brand:  Medchem Express HY-112708A

Product Code. 16424688

Description

Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.

Specifications

• Chemical Name or Material: Brepocitinib P-Tosylate
• Color: White
• Molecular Formula: C₂₅H₂₉F₂N₇O₄S
• Synonym: PF-06700841 P-Tosylate
• SMILES: O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.O=S(C6=CC=C(C)C=C6)(O)=O
• Formula Weight: 561.6
• Grade: Research
• For Use With (Application): COVID-19-immunoregulation

• CAS: 2140301-96-6
• Purity Grade Notes: Research
• Quantity: 10 mg
• Solubility Information: DMSO : 62.5 mg/mL (111.29 mM; Need ultrasonic)
• Molecular Weight (g/mol): 561.6
• Percent Purity: 99.69%
• Physical Form: Solid

Research purposes only