Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)

Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.

Brand:  Thermo Scientific™ 21585

Product Code. 11841245

Description

Thermo Scientific™ Pierce BS3 (Sulfo-DSS) is bis(sulfosuccinimidyl)suberate, an amine-to-amine crosslinker that is homobifunctional, water-soluble, non-cleavable and membrane impermeable.

Highlights:

• Crosslink cell-surface proteins before cell lysis and immunoprecipitation
• Identify receptor-ligand interactions by chemical crosslinking
• “Fix” protein interactions to allow identification of weak or transient protein interactions
• Identify near-neighbor protein interactions
• Protein crosslinking to create bioconjugates via single-step reactions
• Immobilize proteins onto amine-coated surfaces

Specifications

• Chemical Reactivity: Amine-to-Amine
• Formulation: Bis(sulfosuccinimidyl) suberate; solid
• Molecular Weight (g/mol): 572.43
• Sufficient For: 28mL of typical 1X (1mM) reaction solution (total), or 8 separate uses
• Quantity: 8 x 2 mg

• Cleavable: No
• Membrane Permeable: No
• PEGylated: No
• Spacer Arm Length: 11.4Å
• Solubility: Water

For Research Use Only. Not for use in diagnostic procedures.