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Eurofins DiscoverX BTK (E41K) Protein, Active

Product Code. 17370694
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17370694

Brand: Eurofins DiscoverX 14773M

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This item is not returnable. View return policy

Description

Active, N-terminal His6-tagged, recombinant, full-length, human BTK, for use in Kinase Assays.

BTK (Bruton Tyrosine Kinase) is a non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. BTK also plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway.

GenBank NM_000061

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 78.4 kDa
Quantity 250 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
Expression System Recombinant protein expressed in Sf21 insect cells
Protein Form Full-length
Purity or Quality Grade ≥28%
Protein BTK (E41K), active
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