Butyryl chloride, 98%, Thermo Scientific Chemicals

Description

Butyryl chloride is used as an intermediate for the synthesis of active pharmaceutical ingredients benzoyl peroxide, t-butyl perbenzoate, and benzophenone. It is also used as an acylation reagent. Further, it is used in the preparation of peroxides such as benzoyl peroxide, benzophenone and t-butyl perbenzoate. In addition to this, it is involved in the preparation of chromones and antiproliferative agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Butyryl chloride is used as an intermediate for the synthesis of active pharmaceutical ingredients benzoyl peroxide, t-butyl perbenzoate, and benzophenone. It is also used as an acylation reagent. Further, it is used in the preparation of peroxides such as benzoyl peroxide, benzophenone and t-butyl perbenzoate. In addition to this, it is involved in the preparation of chromones and antiproliferative agents.

Solubility
Miscible with ether.

Notes
Moisture sensitive. Incompatible with water, alcohols, strong bases and strong oxidizing agents

Specifications

Chemical Identifiers

• CAS: 141-75-3
• Molecular Formula: C4H7ClO
• Molecular Weight (g/mol): 106.55
• MDL Number: MFCD00000752
• InChI Key: DVECBJCOGJRVPX-UHFFFAOYSA-N
• Synonym: butyryl chloride, n-butyryl chloride, butyric acid chloride, butyroyl chloride, butyric chloride, butyrylchloride, unii-2xvm8e16ir, ccris 5989, n-butyric acid chloride, n-butanoyl chloride
• PubChem CID: 8855
• IUPAC Name: butanoyl chloride
• SMILES: CCCC(Cl)=O

• Melting Point: -89°C
• Density: 1.026
• Boiling Point: 101°C to 102°C
• Flash Point: 18°C (64°F)
• Odor: Acrid
• Refractive Index: 1.412
• Quantity: 50 g
• UN Number: UN2353
• Beilstein: 605395
• Sensitivity: Moisture sensitive
• Merck Index: 14,1598
• Solubility Information: Miscible with ether.
• Formula Weight: 106.55
• Percent Purity: 98%
• Chemical Name or Material: Butyryl chloride

Safety and Handling

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 2
• Substances and mixtures corrosive to metals Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H290-May be corrosive to metals.
• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H331-Toxic if inhaled.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

RUO – Research Use Only