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Thermo Scientific™ TheraPure™ Bz-dC Phosphoramidite, serum vial bottle

Bz-dC CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxycytidine (dC) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-2032-12

Additional Details : Weight : 0.04700kg

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Product Code. 17937152

  • £8.11 / 1g
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Description

Description

Bz-dC CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxycytidine (dC) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis. DNA phosphoramidites are the building blocks for synthesis of DNA or DNA containing oligonucleotides. Each base has unique protecting groups designed specifically to protect the DNA during the chemical synthesis process, and produce the highest amount of full length product. Alternative protecting groups on dC (acetyl) and dG (DMF) allow for a faster deprotection of the oligonucleotide. The TheraPure trademark denotes a highest level of phosphoramidite purity, developed with the highest stringency of of high definiteion analytics and tightly controlled impurity profiles. Ideal for any therapeutic application. This product is supplied in a 60 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems|AKTA Systems of oligonucleotide synthesizers.

Features:
Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Molecular formula: C46H52N5O8P
Base: dC
Base Protection: Bz
Formula weight: 833.93 g/mol
CAS number: 102212-98-6
HPLC Purity: ≥99%; M-11 Impurity ≤0.01%; Single critical impurity ≤0.3%; Presence of dA, dG, or T impurity ≤0.03%
31P NMR Purity: ≥99%; Sum of non-primary peaks at 140-152 ppm: ≤0.3%; No peak(s) above 170 ppm; HMT impurity (∼146ppm): ≤0.10%

Specifications

Specifications

AKTA Synthesizers, Applied Biosystems Synthesizers
Store in freezer (at or below -20°C).
Room Temperature
1 g
TheraPure™
TheraPure™
Bz-dC CEP
Deoxycytidine (dC)
99%
Phosphoramidite
DNA
Powder
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