Tocris Bioscience™ c-Di-GMP sodium salt

Endogenous STING and DDX41 agonist; activates STING-dependent signaling

Brand:  Tocris Bioscience™ 5900/730U

Product Code. 18764868

Description

c-Di-GMP sodium salt is an endogenous STING and DDX41 agonist; mediates DDX41-STING interaction. Activates STING-dependent IFN-β production in mouse and human cells. Also induces an antitumor response in a lung B16-10 melanoma mouse model, when administered intravenously within YSKO5-liposomes.

This product is sold in units of 730μg, equivalent to 1μmol.

Specifications

• Chemical Name or Material: 3′,5′-Cyclic diguanylic acid sodium salt
• Quantity: 730 μg
• Molecular Formula: C₂₀H₂₂N₁₀Na₂O₁₄P₂
• Purity: >98%

• Synonym: endoplasmic reticulum IFN stimulator, Endoplasmic reticulum interferon stimulator, ERIS, FLJ38577, hMITA, Mediator of IRF3 activation, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membr
• Target: STING/TMEM173
• Formula Weight: 734.37