SMAD5 Monoclonal Antibody (ZS004), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen 395700

Product Code. 10642384

Description

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.

Specifications

• Antigen: SMAD5
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: P97454, Q99717, Q9R1V3
• Gene Symbols: SMAD5
• Immunogen: Recombinant protein derived from an internal region of the human and rat Smad5 proteins
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: ZS004
• Conjugate: Unconjugated
• Gene: SMAD5
• Gene Alias: 1110051M15Rik; AI451355; DKFZp781C1895; DKFZp781O1323; dwarfin-C; DWFC; Dwf-C; hSmad5; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; Madh5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 5; mSmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5; SMAD5
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 17129, 4090, 59328
• Content And Storage: -20°C
• Form: Liquid