CA125 Monoclonal Antibody (X325), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA174328

Product Code. 11560582

Description

MA1-74328 recognizes the epitope specificity group B, similar to the M-11 antibody. A suggested positive control for immunohistochemical applications is lung adenocarcinoma, serosal ovarian adenocarcinoma or urinary bladder adenocarcinoma tissue.

CA 125 determinant is present on a high molecular weight, mucin like glycoprotein of high molecular weight. CA 125 has been found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium and peritoneum. In adult tissues, epithelial cells of fallopian tube, endometrium and endocervix; pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland and mammary gland. It is also found in mesothelial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear cell types and adenocarcinomas of mullerian type.

Specifications

• Antigen: CA125
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with <0.1% sodium azide
• Gene Accession No.: Q8WXI7
• Gene Symbols: MUC16
• Immunogen: CA125 antigen purified from human ovarian carcinoma.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: X325
• Conjugate: Unconjugated
• Gene: MUC16
• Gene Alias: 1110008I14Rik; Ca125; CA-125; CA125 ovarian cancer antigen; ca-ovarian; FLJ14303; Gm1480; MUC16; MUC-16; mucin 16; mucin 16, cell surface associated; mucin-16; Ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125; RGD1308422
• Host Species: Mouse
• Purification Method: Ion-exchange chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 94025
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid