CA19-9 Monoclonal Antibody (121SLE), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA513275

Product Code. 11364813

Description

MA5-13275 targets CA19-9 in IHC (P) applications and shows reactivity with Human samples. The MA5-13275 immunogen is mucins from ovarian cyst.

Mucin glycoprotein is a Sialyl Lewis A structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis A and/or Lewis B blood group antigens. In normal tissues, sialyl Lewis A antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings.

Specifications

• Antigen: CA19-9
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Host Species: Mouse
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM

• Applications: Immunohistochemistry (Paraffin)
• Clone: 121SLE
• Conjugate: Unconjugated
• Gene Alias: CA19 9; CA19.9; CA-19.9
• Immunogen: Mucins from ovarian cyst
• Quantity: 500 μL
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Form: Liquid