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Capsazepine, 98+%, Thermo Scientific™ Product Code.: 15415329
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Capsazepine, 98+%, Thermo Scientific™

Product Code. 15415329
50mg
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Quantity:
10mg
50mg
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Product Code. 15415329

Brand: Thermo Scientific Alfa Aesar J63055.MF

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Description

A competitive antagonist for capsaicin and resiniferatoxin

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

Solubility
Soluble in ethanol or DMSO

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 138977-28-3
Molecular Formula C19H21ClN2O2S
Molecular Weight (g/mol) 376.899
MDL Number MFCD00153778
InChI Key DRCMAZOSEIMCHM-UHFFFAOYSA-N
Synonym capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464Show MoreShow Less
PubChem CID 2733484
ChEBI CHEBI:70773
IUPAC Name N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
SMILES C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O

Specifications

Quantity 50mg
Solubility Information Soluble in ethanol or DMSO
Formula Weight 376.9
Percent Purity ≥99%
Chemical Name or Material Capsazepine

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberZ21E031 Certificate TypeCertificate of Analysis Date08/12/2021 Catalog NumberJ63055.MA,J63055.MF
Lot NumberP24B042 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberJ63055.MA,J63055.MF
Lot NumberM29F043 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberJ63055.MA,J63055.MF
Lot NumberY05F098 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberJ63055.MA,J63055.MF
Lot NumberX31F043 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberJ63055.MA,J63055.MF

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