Carbamazepine, Tocris Bioscience™

Description

Inhibitor of neuronal voltage-gated Na+ channels; anticonvulsant

Inhibitor of neuronal voltage-gated Na+ channels. Exhibits anticonvulsant activity. Potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor α1β2γ2 subtype combination. Can induce autophagy by inhibiting inositol synthesis. Also delays disease onset and prolongs survival in a mouse amyotrophic lateral sclerosis (ALS) model, as well as reducing motor neuron loss and altered muscle morphology.

Specifications

• CAS: 298-46-4
• Molecular Formula: C15H12N2O
• MDL Number: MFCD00005073
• Quantity: 50 mg
• Synonym: carbamazepine, tegretol, 5h-dibenzo b,f azepine-5-carboxamide, carbamazepen, carbazepine, finlepsin, carbamezepine, equetro, tegretal, biston
• InChI Key: FFGPTBGBLSHEPO-UHFFFAOYSA-N
• SMILES: NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
• IUPAC Name: 2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,9,11,13-heptaene-2-carboxamide
• Molecular Weight (g/mol): 236.27
• PubChem CID: 2554
• ChEBI: CHEBI:3387
• Formula Weight: 236.27
• Percent Purity: >99%
• Chemical Name or Material: Carbamazepine