Thermo Scientific Chemicals Caspase-3 Inhibitor III

Product Code	Brand	Quantity
15456389	Thermo Scientific Chemicals J64442.M^	1 mg
15446389	Thermo Scientific Chemicals J64442.#0	5 mg

Description

A potent, cell-permeable, and irreversible inhibitor of caspase-3; also inhibits caspases -6, -7, -8, and -10. Commonly used at concentrations up to 100 -M to examine the role of caspase-3-dependent apoptosis

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

• CAS: 285570-60-7
• Molecular Formula: C21H31ClN4O11
• Synonym: Ac-DEVD-CMK; N-Acetyl-Asp-Glu-Val-Asp chloromethyl ketone

Specifications

• Description: Off-white to brown
• For Use With (Application): A potent, cell-permeable, and irreversible inhibitor of caspase-3; also inhibits caspases -6, -7, -8, and -10. Commonly used at concentrations up to 100 →M to examine the role of caspase-3-dependent apoptosis
• Molecular Formula: C21H31ClN4O11
• Synonym: Ac-DEVD-CMK; N-Acetyl-Asp-Glu-Val-Asp chloromethyl ketone
• Form: Powder
• SMILES: CC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(C)=O)C(=O)NC(CC(O)=O)C(=O)CCl
• Molecular Weight (g/mol): 550.95

• Content And Storage: -30°C to -10°C
• CAS: 285570-60-7
• Formula Weight: 550.94
• Solubility: Soluble in DMSO
• InChI Key: ATNOUPFYBMVFLD-UHFFFAOYNA-N
• IUPAC Name: 3-{2-[4-carboxy-2-(3-carboxy-2-acetamidopropanamido)butanamido]-3-methylbutanamido}-5-chloro-4-oxopentanoic acid

Safety and Handling

Recommended Storage : Store at -20°C

RUO – Research Use Only