STEMCELL Technologies CAY10603

Epigenetic modifier; Inhibits histone deacetylase (HDAC) 6

Brand:  STEMCELL Technologies 73582

Product Code. 17190242

Description

• CAY10603 is a selective and potent inhibitor of histone deacetylase 6 (HDAC6; IC₅₀ = 0.002 nM; Kozikowski et al.) HDAC6 deacetylates lysine residues on the N-terminal part of histones
• HDAC6 is also known to regulate heat shock protein 90 (hsp90) via hyperacetylation (Rao et al.)
• Inhibits growth of several pancreatic cancer cell lines (IC₅₀ = 0.1 - 1 μM) and SCCOHT, an ovarian cancer cell line (Kozikowski et al.; Wang et al.)

Specifications

• CAS: 1045792-66-2
• Quantity: 1 mg
• Purity: ≥95%

• Synonym: HDAC6 inhibitor
• Molecular Formula: C₂₂H₃₀N₄O₆