CCR9 (extracellular) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5111768

Product Code. 17149683

Description

Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Peptide sequence is: (C)DESTKLK SAVLTLK Homology: Mouse, rat - 10/14 amino acid residues identical.

The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.

Specifications

• Antigen: CCR9 (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ccr9
• Gene Alias: A130091K22Rik; C-C chemokine receptor type 9; C-C CKR-9; CC-CKR-9; CCR9; CDw199; CDw199 antigen; Chemokine C-C receptor 10; Cmkbr10; GPR28; GPR-9-6; G-protein coupled receptor 28
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10803, 12769, 282832
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P51686, Q9WUT7
• Gene Symbols: Ccr9
• Immunogen: Peptide corresponding to amino acid residues 205-218 of human CCR9 (2nd extracellular loop)
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG