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CD137 Polyclonal Antibody, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

£165.00 - £1374.00

Specifications

Antigen CD137
Concentration 0.1-1.0 mg/mL
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17834413
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Invitrogen
500-P167G-50UG
50 μg
£165.00
50µg
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17884673
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Invitrogen
500-P167G-100UG
100 μg
£212.00
100µg
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17804083
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Invitrogen
500-P167G-1MG
1 mg
£1374.00
1mg
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Description

Description

AA Sequence of recombinant protein: MERTRSLQDP CSNCPAGTFC DNNRNQICSP CPPNSFSSAG GQRTCDICRQ CKGVFRTRKE CSSTSNAECD CTPGFHCLGA GCSMCEQDCK QGQELTKKGC KNCCFGTFND QKRGICRPWT NCSLDGKSVL VNGTKERDVV CGPSPADLSP GASSVTPPAP AREPGHS. Preparation: Produced from sera of goats immunized with highly pure Recombinant Human 4-1BB Receptor. Anti-Human 4-1BB Receptor-specific antibody was purified by affinity chromatography employing an immobilized Human 4-1BB Receptor matrix. Sandwich ELISA: To detect Human 4-1BB Receptor by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human 4-1BB Receptor (500-P167GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human 4-1BB Receptor. Western Blot: To detect Human 4-1BB Receptor by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human 4-1BB Receptor is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
Specifications

Specifications

CD137
ELISA, Western Blot
Unconjugated
Goat
Human
Q07011
3604
E.coli-derived Recombinant Human 4-1BB Receptor
Antigen affinity chromatography
TNFRSF9
0.1-1.0 mg/mL
Polyclonal
Lyophilized
RUO
PBS with no preservative
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
TNFRSF9
Primary
-20°C
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