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CD23 Monoclonal Antibody (B3B4), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£74.25 - £185.00
Specifications
Antigen | CD23 |
---|---|
Clone | B3B4 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | PerCP-eFluor 710 |
Description
CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma.
CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.Specifications
CD23 | |
Flow Cytometry | |
PerCP-eFluor 710 | |
Rat | |
Mouse | |
14128 | |
IgG2a κ | |
Affinity chromatography | |
Fcer2a |
B3B4 | |
Monoclonal | |
Liquid | |
RUO | |
P20693 | |
Fcer2a | |
Primary | |
Antibody |
For Research Use Only.