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CD24 Monoclonal Antibody (eBioSN3 (SN3 A5-2H10)), Biotin, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen 13-0247-80
Description
Description: The SN3 monoclonal antibody reacts with the human CD24 molecule, also known as Heat Stable Antigen (HSA). This 35-50 kDa molecule is anchored in the plasma membrane via phosphatidylinositol and is expressed by erythrocytes, thymocytes, peripheral lymphocytes and myeloid lineage. It has been reported that P-selectin (CD62P) binds to CD24. Applications Reported: This eBioSN3 (SN3 A5-2H10) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioSN3 (SN3 A5-2H10) antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.
CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin′s lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, and control of autoimmunity.Specifications
CD24 | |
Monoclonal | |
0.5 mg/mL | |
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2 | |
P25063 | |
CD24 | |
Affinity chromatography | |
RUO | |
100133941 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
eBioSN3 (SN3 A5-2H10) | |
Biotin | |
CD24 | |
CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24A; FLJ22950; FLJ43543; MGC75043 | |
Mouse | |
25 μg | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
For Research Use Only.