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CD38 Monoclonal Antibody (90), Brilliant Violet™ 480, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£136.00 - £316.00

Specifications

Antigen CD38
Clone 90
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17817502
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Invitrogen
414-0381-80
25 μg
£136.00
25µg
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17837302
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Invitrogen
414-0381-82
100 μg
£316.00
100µg
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Description

Description

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.
Specifications
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CD38 Monoclonal Antibody (90), Brilliant Violet™ 480, eBioscience™, Invitrogen™

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