Learn More
CD68 Monoclonal Antibody (FA-11), PE-Cyanine7, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£127.00 - £294.00
Specifications
Antigen | CD68 |
---|---|
Clone | FA-11 |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15548426
|
Invitrogen
25-0681-80 |
25 μg |
£127.00
25µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
15558426
|
Invitrogen
25-0681-82 |
100 μg |
£294.00
100µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Description: This FA-11 monoclonal antibody reacts with mouse CD68, known also as macrosialin. CD68 is a heavily O- and N- glycosylated type I integral membrane protein belonging to the sialomucin family and is closely related to the Lysosomal/endosomal-Associated Membrane Glycoproteins (LAMP). Although commonly used as a pan-macrophage marker, low levels of expression have also been observed in Langerhans cells and conventional dendritic cells. CD68 is mostly localized in the late endosomes and lysosomes with a smaller fraction circulating to the cell surface. In the steady state, only about 10-15% of CD68 is present at the surface. Cell stimulation increases expression of CD68, its transport to cell surface, and results in glycoform remodeling. CD68 binds oxidized LDL and is involved in the process of phagocytosis. The FA-11 antibody is not recommended for use in immunohistochemistry of formalin-fixed paraffin embedded tissues. Applications Reported: This FA-11 antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This FA-11 antibody has been tested by intracellular staining and flow cytometric analysis of mouse bone marrow-derived macrophages using the Intracellular Fixation & Permeabilization Buffer Set (cat. 88-8824) and protocol. Please refer to Best Protocols: Protocol A: Two step protocol for (cytoplasmic) intracellular proteins located under the Resources Tab online.
CD68 Monoclonal antibody specifically detects CD68 in Mouse samples. It is validated for Flow Cytometry.Specifications
CD68 | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen | |
Cd68 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Cd68 |
FA-11 | |
Flow Cytometry | |
PE-Cyanine7 | |
Rat | |
Mouse | |
P31996 | |
12514 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.