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CD87 (UPAR) Monoclonal Antibody (VIM5), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£306.00
Specifications
Antigen | CD87 (UPAR) |
---|---|
Clone | VIM5 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | PerCP-eFluor 710 |
Description
Description: This VIM5 monoclonal antibody reacts with human CD87, a GPI-linked receptor for urokinase plasminogen activator (uPA). By sequestering uPA, CD87 is involved in the conversion of plasminogen to plasmin on the leading edge of migrating cells, a process critical for chemotaxis. CD87 is expressed on the surface of monocytes, dendritic cells, and on activated T and NK cells. Interestingly, in granulocytes, CD87 expressed in the cytoplasm and on the cell surface. Non-hematopoietic cells such as endothelial cells, keratinocytes, and fibroblasts, also express this receptor. Finally, CD87 plays a role in cell adhesion and migration, angiogenesis, and tumor metastasis. This monoclonal antibody has been reported to have neutralization activity. Applications Reported: This VIM5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This VIM5 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. PerCP-eFluor™ 710 emits at 710 nm and is excited with the blue laser (488 nm); it can be used in place of PerCP-Cyanine5.5.
CD87 (UPAR) Monoclonal antibody specifically detects CD87 (UPAR) in Human samples. It is validated for Flow Cytometry.Specifications
CD87 (UPAR) | |
Flow Cytometry | |
PerCP-eFluor 710 | |
Mouse | |
Human | |
Q03405 | |
PLAUR | |
Primary | |
Antibody |
VIM5 | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
5329 | |
IgG1 κ | |
Affinity chromatography | |
PLAUR |
For Research Use Only.