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CDKN2C Monoclonal Antibody (18P118 (DCS-118)), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA514282
Code : LE
Additional Details : Weight : 0.01000kg
Description
MA5-14282 targets p18INK4c in IF, IHC (P), IP, and WB applications and shows reactivity with Human and mouse samples. The MA5-14282 immunogen is purified recombinant p18INK4c protein.
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.Specifications
| CDKN2C | |
| Monoclonal | |
| 0.4 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P42773, Q60772 | |
| CDKN2C | |
| Purified recombinant p18INK4c protein | |
| 500 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 18P118 (DCS-118) | |
| Unconjugated | |
| CDKN2C | |
| C77269; CDK6 inhibitor p18; Cdkn2c; CDKN6; cyclin dependent kinase inhibitor 2C; cyclin-dependent inhibitor; cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase 6 inhibitor p18; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); INK4c; p18; p18INK4c; p18-INK4c; p18-INK6 | |
| Mouse | |
| Protein G | |
| RUO | |
| 1031, 12580 | |
| 4° C | |
| Liquid |