Celecoxib, Tocris Bioscience™

Description

Selective cyclooxygenase-2 (COX-2) inhibitor

Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). Celecoxib is an anti-inflammatory with shorter plasma half-life in vivo than SC 58121. Displays chemopreventive activity in in vivo tumor models.

Specifications

Chemical Identifiers

• CAS: 169590-42-5
• Molecular Formula: C17H14F3N3O2S
• Molecular Weight (g/mol): 381.373
• InChI Key: RZEKVGVHFLEQIL-UHFFFAOYSA-N
• Synonym: celecoxib, celebrex, celebra, onsenal, celocoxib, celecox, xilebao, 4-5-4-methylphenyl-3-trifluoromethyl-1h-pyrazol-1-yl benzenesulfonamide, celecoxib usan, celecoxib old rn
• PubChem CID: 2662
• ChEBI: CHEBI:41423
• IUPAC Name: 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
• SMILES: CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F

• Quantity: 10 mg
• Formula Weight: 381.37
• Percent Purity: >99%
• Chemical Name or Material: Celecoxib