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  6. CGP 3466B maleate, Tocris Bioscience™

CGP 3466B maleate, Tocris Bioscience™

Product Code. 18094192
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

GAPDH inhibitor; neuroprotective

CGP 3466B maleate is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. Exhibits antiapoptotic activity via inhibition of GAPDH nuclear translocation and mitochondrial complex 1-dependent H2O2 release. CGP 3466B inhibits colon cancer proliferation in vitro and displays neuroprotective activity in vivo.

Chemical Identifiers

CAS 200189-97-5
Molecular Formula C23H21NO5
Molecular Weight (g/mol) 391.423
InChI Key SQAZQLMBEHYFJA-BTJKTKAUSA-N
Synonym omigapil maleate, cgp 3466b maleate, unii-3q69bfz4op, 3q69bfz4op, tch 346 maleate, dibenzo b,f oxepin-10-ylmethyl-methyl-prop-2-ynyl-amine maleate, n-dibenz b,f oxepin-10-ylmethyl-n-methyl-n-2-propynyl amine monomaleic acid salt, n-dibenz b,f oxepin-10-ylmethyl-n-methyl-n-2-propynyl amine maleate, maleic acid; methyl 2-oxatricyclo 9.4.0.0 3 ,? pentadeca-1 15 ,3 8 ,4,6,9,11,13-heptaen-9-ylmethyl prop-2-yn-1-ylamine
PubChem CID 9821821
IUPAC Name N-(benzo[b][1]benzoxepin-5-ylmethyl)-N-methylprop-2-yn-1-amine;(Z)-but-2-enedioic acid
SMILES CN(CC#C)CC1=CC2=CC=CC=C2OC3=CC=CC=C31.C(=CC(=O)O)C(=O)O

Specifications

Quantity 50 mg
Formula Weight 391.42
Percent Purity >99%
Chemical Name or Material CGP 3466B maleate
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