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Invitrogen™ Chicken IL-10 ELISA Kit
Chicken IL-10 quantitates chicken IL-10 in serum, plasma, supernatant.
£528.00 - £3870.00
Especificaciones
Accession Number | CSIF; cytokine; cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; Interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF |
---|---|
Assay Range | 16 to 3,500 pg/mL |
Assay Sensitivity | 16 pg/mL |
Conjugate | Biotin |
Product Type | ELISA |
Código de producto | Marca | Quantity | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Quantity | Precio | Cantidad y disponibilidad | |||||
17182189
|
Invitrogen™
ECH3RBX5 |
5 x 96 Tests |
£2320.00
Each |
Estimated Shipment: 02-08-2024
Log in to see stock. |
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17804050
|
Invitrogen™
ECH3RBX10 |
10 x 96 Tests |
£3870.00
Pack of 10 |
Estimated Shipment: 20-08-2024
Log in to see stock. |
|||||
17144353
|
Invitrogen™
ECH3RB |
96 Tests |
£528.00
Pack of 96 |
Estimated Shipment: 20-08-2024
Log in to see stock. |
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Descripción
Chicken IL-10 quantitates chicken IL-10 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant chicken IL-10.
Interleukin 10 (IL-10, CSIF) is an anti-inflammatory cytokine mainly produced by macrophages and Th2 cells. IL-10 is an 18.6 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein (BCRFI). The reported biological activities of IL-10, which maybe interrelated, include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed-type hyper-sensitivity response, and stimulation of the Th2 cell response which results in elevated antibody production. IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including IFN-gamma, TNF-alpha, IL-2, and IL-3, IL-4, and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells, enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. While human IL-10 can act on murine cells, murine IL-10 cannot act on human cells. Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). IL-10 inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Knockout studies in mice suggest the function of this cytokine as an essential immunoregulator in the intestinal tract.Especificaciones
CSIF; cytokine; cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; Interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF | |
16 pg/mL | |
ELISA | |
Colorimetric Microplate Reader | |
IL10 | |
<10% | |
HRP | |
Serum, 50 μL; Plasma, 50 μL; Supernatant, 50 μL | |
IL-10 | |
4 hr 45 min |
16 to 3,500 pg/mL | |
Biotin | |
Plasma, Serum, Supernatant | |
Q6A2H4 | |
<12% | |
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
Research Use Only | |
2°C to 8°C | |
1 hr 20 min |