Chloroform, 99%, stab. with 0.8-1% ethanol, Thermo Scientific Chemicals

Description

Chloroform is a commonly used laboratory solvent. It was previously used as an anesthetic. It is also used as a precursor to PTFE and refrigerants. Chloroform was used in the past as an extraction solvent for fats, oils and greases. It is useful for the rapid and simple release of periplasmic proteins. The mixture of guanidinium thiocyanate-phenol-chloroform, plays an essential role in the RNA isolation process.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chloroform is a commonly used laboratory solvent. It was previously used as an anesthetic. It is also used as a precursor to PTFE and refrigerants. Chloroform was used in the past as an extraction solvent for fats, oils and greases. It is useful for the rapid and simple release of periplasmic proteins. The mixture of guanidinium thiocyanate-phenol-chloroform, plays an essential role in the RNA isolation process.

Solubility
Miscible with diethyl ether, oils, ligroin, alcohol, acetone, carbon tetrachloride and carbondisulfide.Slightly miscible with water.

Notes
It is a stable and light sensitive chemical compound. Incompatible with metals, alkalies. Keep the material away from heat, sparks and flame and other sources of ignition. Store it in a cool, dry, well-ventilated area.

Specifications

Chemical Identifiers

• CAS: 67-66-3
• Molecular Formula: CHCl3
• Molecular Weight (g/mol): 119.37
• MDL Number: MFCD00000826
• InChI Key: HEDRZPFGACZZDS-UHFFFAOYSA-N
• Synonym: trichloromethane, formyl trichloride, methane, trichloro, trichloroform, methane trichloride, methenyl trichloride, methyl trichloride, trichlormethan, chloroforme, cloroformio
• PubChem CID: 6212
• ChEBI: CHEBI:35255
• SMILES: ClC(Cl)Cl

• Melting Point: -63°C
• Density: 1.492
• Boiling Point: 60.5°C to 61.5°C
• Quantity: 500 mL
• Odor: Characteristic
• Refractive Index: 1.444
• UN Number: UN1888
• Beilstein: 1731042
• Merck Index: 14,2141
• Solubility Information: Miscible with diethyl ether,oils,ligroin,alcohol,acetone,carbon tetrachloride and carbondisulfide.Slightly miscible with water.
• IUPAC Name: chloroform
• Formula Weight: 119.38
• Percent Purity: 99%
• Chemical Name or Material: Chloroform, stabilized with 0.8 to 1% ethanol

Safety and Handling

Product Identifier

• Chloroform, stabilized

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• Carcinogenicity Category 2
• Serious eye damage/eye irritation Category 2
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 1
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H331-Toxic if inhaled.
• H336-May cause drowsiness or dizziness.
• H351-Suspected of causing cancer.
• H361d-Suspected of damaging the unborn child.
• H372-Causes damage to organs.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P311-Call a POISON CENTER/doctor/ .

Supplemental information

• MIXTURE LIST-Contains : Chloroform

RUO – Research Use Only