Chloromethyl chloroformate, 97%, Thermo Scientific Chemicals

Description

Chloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A.

Solubility
Slightly miscible with water.

Notes
Incompatible with oxidizing agents and water.

Specifications

• Melting Point: <-20°C
• Density: 1.465
• Boiling Point: 107°C to 108°C
• Flash Point: 95°C (203°F)
• Odor: Acrid
• Linear Formula: ClCO₂CH₂Cl
• Refractive Index: 1.4295
• Quantity: 10 g
• UN Number: UN2745
• Beilstein: 506426
• Sensitivity: Moisture sensitive
• Solubility Information: Slightly miscible with water.
• Formula Weight: 128.94
• Percent Purity: 97%
• Chemical Name or Material: Chloromethyl chloroformate

RUO – Research Use Only