CI 976, Tocris Bioscience™

Beschreibung

Selective ACAT inhibitor

Selective acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor (IC50 = 0.073 μM). Lowers non-high density lipoprotein (HDL)-cholesterol and increases HDL-cholesterol concentrations in rats with pre-established dyslipidemia. Orally active. Also inhibits Golgi-associated LPL acyltransferase (LPAT) activity (IC50 = 15 μM).

Spezifikation

Chemische Identifikatoren

• CAS: 114289-47-3
• Molecular Formula: C23H39NO4
• Molecular Weight (g/mol): 393.568
• InChI Key: WAFNZAURAWBNDZ-UHFFFAOYSA-N
• Synonym: 2,2-dimethyl-n-2,4,6-trimethoxyphenyl dodecanamide, chembl22373, unii-8653iq20ea, dodecanamide,2,2-dimethyl-n-2,4,6-trimethoxyphenyl, dodecanamide, 2,2-dimethyl-n-2,4,6-trimethoxyphenyl, 2,2-dimethyl-dodecanoic acid 2,4,6-trimethoxy-phenyl-amide, acmc-1cuxf, d0d1xg, ci hplc , solid
• PubChem CID: 122327
• IUPAC Name: 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
• SMILES: CCCCCCCCCCC(C)(C)C(=O)NC1=C(C=C(C=C1OC)OC)OC

• Quantity: 10 mg
• Formula Weight: 393.57
• Percent Purity: >98%
• Chemical Name or Material: CI 976