Tocris Bioscience™ CINPA 1

Potent CAR antagonist

Brand:  Tocris Bioscience™ 5605/50

Product Code. 18732739

Description

CINPA 1 is a potent CAR antagonist (IC50 = 70 nM). Exhibits >90-fold selectivity for CAR over pregnane X receptor (PXR). Also selective over a panel of other nuclear receptors including FXR, LXR, PPARγ and RXR.

Specifications

• Chemical Name or Material: Ethyl [5-[(diethylamino)acetyl]-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]carbamate
• Quantity: 50 mg
• Molecular Formula: C₂₃H₂₉N₃O₃
• Purity: >98%

• CAS: 102636-74-8
• Target: Constitutive Androstane Receptor Antagonists
• Formula Weight: 395.49