Cisplatin, Tocris Bioscience™

Description

Potent pro-apoptotic anticancer agent; activates caspase-3

Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF-α-induced apoptosis.

Specifications

• CAS: 15663-27-1
• Quantity: 50 mg
• Molecular Formula: Cl2H6N2Pt
• MDL Number: MFCD00011623
• Synonym: cis-Diaminodichloroplatinum
• InChI Key: BSJGASKRWFKGMV-UHFFFAOYSA-L
• SMILES: N.N.Cl[Pt++]Cl
• IUPAC Name: dichloroplatinumbis(ylium) diamine
• Molecular Weight (g/mol): 300.04
• Formula Weight: 300.05
• Percent Purity: >98%
• Chemical Name or Material: Cisplatin