Clindamycin hydrochloride monohydrate, Thermo Scientific Chemicals

Description

Clindamycin hydrochloride, CAS # 21462-39-5, is the salt of clindamycin, a derivative of the broad-spectrum bacteriostatic antibiotic lincomycin.

Clindamycin hydrochloride monohydrate is an antibacterial agent that is a semisynthetic analog of lincomycin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Clindamycin is a lincosamide antibiotic that disrupts protein synthesis by interfering with the aminoacyl-tRNA ribosome complex

• Clindamycin decreases sebaceous gland activity and blocks the neuromuscular junction

Application

• Clindamycin is commonly used in laboratory applications to inhibit the growth anaerobic microbes, but has some effectiveness against aerobic microbes as well

• It can be used in the laboratory study of cell culture for resistance testing, or in antibiotic allergic reaction studies

Specifications

Chemical Identifiers

• CAS: 58207-19-5
• Molecular Formula: C18H34Cl2N2O5S
• Molecular Weight (g/mol): 461.439
• MDL Number: MFCD07793327
• InChI Key: AUODDLQVRAJAJM-NFOLQJLNSA-N
• PubChem CID: 131632848
• IUPAC Name: (2S,4R)-N-[2-chloro-1-[(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
• SMILES: CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.Cl

• Type: Clindamycin Hydrochloride Monohydrate
• Physical Form: Powder
• Beilstein: 4070786
• Merck Index: 14,2356
• Solubility Information: Soluble in water
• Formula Weight: 479.46 (461.44 Anhydrous)
• Color: White
• Quantity: 1 g
• Chemical Name or Material: Clindamycin hydrochloride monohydrate

Safety and Handling

Product Identifier

• Clindamycin hydrochloride monohydrate

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Clindamycin hydrochloride monohydrate

RUO – Research Use Only