Clotrimazole, Tocris Bioscience™

Description

Cytochrome P450 inhibitor; antifungal

Imidazole antimycotic and cytochrome P450 inhibitor. Inhibits Ca2+-activated K+ current (IC50 = 3 μM) and L-type Ca2+ current; increases the firing rate of action potentials. Exhibits antiproliferative activity in vitro and in vivo. Also an inverse agonist of the human constitutive androstane receptor (hCAR).

Specifications

• CAS: 23593-75-1
• Molecular Formula: C22H17ClN2
• Quantity: 50 mg
• Synonym: clotrimazole, lotrimin, canesten, mycelex, mycosporin, empecid, clotrimazol, mykosporin, gyne lotrimin, chlotrimazole
• InChI Key: VNFPBHJOKIVQEB-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4
• IUPAC Name: 1-[(2-chlorophenyl)-diphenylmethyl]imidazole
• Molecular Weight (g/mol): 344.842
• PubChem CID: 2812
• ChEBI: CHEBI:3764
• Formula Weight: 344.84
• Percent Purity: >99%
• Chemical Name or Material: Clotrimazole