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Tocris Bioscience™ Clozapine N-oxide

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
Metabolite of clozapine (Cat. No. 0444). Activates human muscarinic designer receptors (DREADDs) in vitro. Silences hippocampal neurons expressing hM4 DREADDs in vitro. Activates Gs-linked DREADDS- AgRP in mice via intracerebroventricular (i.c.v) injection. Shown to be a P-glycoprotein (P-gp) efflux pump substrate. Other potent and selective hM3Dq DREADD agonists available: DREADD agonist 21 and Perlapine .
Water soluble salt also available.
This product contains 1 molar equivalent of ethanol.
Specifications
Specifications
| Assay Percent Range | >98% |
| Quantity | 10 mg |
| Formula Weight | 342.82 |
| Purity | >99% |
| Molecular Weight (g/mol) | 342.827 |
| Chemical Name or Material | Clozapine N-oxide |
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