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  7. Clozapine N-oxide, Tocris Bioscience™

Clozapine N-oxide, Tocris Bioscience™

Catalog Number 30001355
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
34233-69-7
C18H19ClN4O
342.827
WYRDWWAASBTJLM-UHFFFAOYSA-N
clozapine n-oxide, clozapine-n-oxide, unii-mza8bk588j, chembl1688, mza8bk588j, n-oxyclozapine, clozapine n-oxide cno, oguczbiqsyywef-uhfffaoysa-n
2819
3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-]
This item is not returnable. View return policy
34233-69-7
C18H19ClN4O
342.827
WYRDWWAASBTJLM-UHFFFAOYSA-N
clozapine n-oxide, clozapine-n-oxide, unii-mza8bk588j, chembl1688, mza8bk588j, n-oxyclozapine, clozapine n-oxide cno, oguczbiqsyywef-uhfffaoysa-n
2819
3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-]

Description

Activator of muscarinic DREADDs

Metabolite of clozapine (Cat. No. 0444). Activates human muscarinic designer receptors (DREADDs) in vitro. Silences hippocampal neurons expressing hM4 DREADDs in vitro. Activates Gs-linked DREADDS- AgRP in mice via intracerebroventricular (i.c.v) injection. Shown to be a P-glycoprotein (P-gp) efflux pump substrate. Other potent and selective hM3Dq DREADD agonists available: DREADD agonist 21 and Perlapine .

Water soluble salt also available.

This product contains 1 molar equivalent of ethanol.

Assay Percent Range >98%
Quantity 10 mg
Formula Weight 342.82
Percent Purity >99%
Chemical Name or Material Clozapine N-oxide
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