Tocris Bioscience™ CMPD-1

Selective inhibitor of p38α-mediated MK2a phosphorylation; also tubulin polymerization inhibitor

Brand:  Tocris Bioscience™ 2186/50

Product Code. 18084522

Description

CMPD-1 is a non-ATP-competitive, selective inhibitor of p38α-mediated MK2a (mitogen-activated protein kinase-2a) phosphorylation (apparent Ki = 330 nM). Does not inhibit p38α-mediated phosphorylation of MBP and ATF-2. Also tubulin polymerization inhibitor. Cytotoxic in glioblastoma cells at concentrations that do not affect the MK2 pathway.

Specifications

• Purity: >99%
• Product Type: CMPD-1
• Inhibitors: CMPD-1

• Quantity: 50 mg
• Molecular Weight (g/mol): 349.4

For Research Use Only