Coenzyme Q-10, 98+%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
15456749	Thermo Scientific Alfa Aesar J65137.03	1 g
15466749	Thermo Scientific Alfa Aesar J65137.06	5 g
15476749	Thermo Scientific Alfa Aesar J65137.14	25 g

Description

It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

Solubility
Soluble in chloroform.

Notes
Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Chemical Identifiers

• CAS: 303-98-0
• Molecular Weight (g/mol): 863.37
• InChI Key: ACTIUHUUMQJHFO-UPTCCGCDSA-N
• PubChem CID: 5281915
• SMILES: COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O

• Molecular Formula: C59H90O4
• MDL Number: MFCD00042919
• Synonym: coenzyme q10, ubidecarenone, ubiquinone 50, coq10, ubiquinone-10, neuquinon, ubiquinone, justquinon, neuquinone, emitolon
• ChEBI: CHEBI:46245

Specifications

• CAS: 303-98-0
• Color: Yellow to Orange
• MDL Number: MFCD00042919
• Sensitivity: Light sensitive
• Synonym: coenzyme q10, ubidecarenone, ubiquinone 50, coq10, ubiquinone-10, neuquinon, ubiquinone, justquinon, neuquinone, emitolon
• InChI Key: ACTIUHUUMQJHFO-UPTCCGCDSA-N
• IUPAC Name: 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
• PubChem CID: 5281915
• Formula Weight: 863.36
• Physical Form: Powder

• Melting Point: 48°C to 52°C
• Molecular Formula: C59H90O4
• Beilstein: 1900141
• Merck Index: 14,9843
• Solubility Information: Soluble in chloroform.
• SMILES: COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O
• Molecular Weight (g/mol): 863.37
• ChEBI: CHEBI:46245
• Percent Purity: ≥98%
• Chemical Name or Material: Coenzyme Q-10

Safety and Handling

missing translation for 'einecsNumber' : 206-147-9

missing translation for 'rtecsNumber' : DK3900000

missing translation for 'tsca' : Yes

Recommended Storage : Store at -20°C

RUO – Research Use Only