Thermo Scientific Chemicals Colistin sulfate salt

Product Code. 15575146

Brand: Thermo Scientific Chemicals 455392500

Description

Colistin Sulfate salt (2:5), CAS # 1264-72-8, (synonym: Polymyxin E Complex), is a complex mixture of antibiotics, with Colistin A and B being the primary components. It has anti-bacterial activity against Gram-positive and Gram-negative bacteria and may also be used as a neuromuscular blocker.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• Colistin Sulfate salt is a stable, cationic, water-soluble, white powder composed of over 30 components
• Originally isolated from B. polymyxa, it inhibits the growth of the Gram-negative (e.g. E. coli, P. aeruginosa, P. fluorescens, and S. enterica), and Gram-positive bacteria (e.g. L. lactis, P. polymyxa, P. acidilactici, and S. aureus) by permeabilizing the bacterial cell membrane

Applications
• Colistin Sulfate has potent anti-endotoxin activity rendered through its ability to bind lippopolysaccharides that make up bacterial endotoxins
• This compound is often used in the management of multi-drug resistant Gram-negative infections

Specifications

Chemical Identifiers

• CAS: 1264-72-8

• Type: Colistin Sulfate salt
• Quantity: 250 mg
• Solubility Information: Solubility in water: soluble. Other solubilities: slightly soluble in methanol, insoluble in acetone, diethyl ether
• Percent Purity: ≥77% Sum of Polymyxins (HPLC)
• Chemical Name or Material: Colistin sulfate salt

Safety and Handling

Product Identifier

• Colistin sulfate salt

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3

Hazard Statement

• H301-Toxic if swallowed.

Precautionary Statement

• P264-Wash thoroughly after handling.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /

SDS

RUO – Research Use Only