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CXCL11 Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
£165.00 - £1374.00
Specifications
Antigen | CXCL11 |
---|---|
Concentration | 0.1-1.0 mg/mL |
Applications | ELISA, Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17834143
|
Invitrogen
500-P132-50UG |
50μg |
£165.00
50µg |
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17854653
|
Invitrogen
500-P132-100UG |
100 μg |
£212.00
100µg |
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17854083
|
Invitrogen
500-P132-1MG |
1 mg |
£1374.00
1mg |
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Description
AA Sequence of recombinant protein: FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human I-TAC (CXCL11). Anti-Human I-TAC (CXCL11)-specific antibody was purified by affinity chromatography employing an immobilized Human I-TAC (CXCL11) matrix. Sandwich ELISA: To detect Human I-TAC (CXCL11) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human I-TAC (CXCL11) (500-P132Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human I-TAC (CXCL11). Western Blot: To detect Human I-TAC (CXCL11) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human I-TAC (CXCL11) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.Specifications
CXCL11 | |
ELISA, Western Blot | |
Unconjugated | |
Rabbit | |
Human | |
O14625 | |
6373 | |
E.coli-derived Recombinant Human I-TAC (CXCL11) | |
Antigen affinity chromatography | |
CXCL11 |
0.1-1.0 mg/mL | |
Polyclonal | |
Lyophilized | |
RUO | |
PBS with no preservative | |
betaR1; beta-R1; b-R1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 11; CXC; CXC motif chemokine; C-X-C motif chemokine 11; C-X-C motif chemokine ligand 11; Cxc11; CXCL; CXCL11; H174; Interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; IP9; IP-9; Itac; I-TAC; MGC102770; Scyb11; Scyb9b; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; small-inducible cytokine B11 | |
CXCL11 | |
Primary | |
-20°C |