Thermo Scientific Chemicals Cyclosporin A, 98%

Description

Cyclosporin A, 98%, CAS # 59865-13-3, is a compound that shows immunosuppressive, antifungal, antirheumatic, and dermatologic activities. It is also a calcineurin and enzyme inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Cyclosporin A is a non-polar cyclic oligopeptide produced by the fungus Tolypocladium inflatum

Specifications

Chemical Identifiers

• CAS: 59865-13-3
• Molecular Formula: C62H111N11O12
• Molecular Weight (g/mol): 1202.64
• MDL Number: MFCD00274558
• InChI Key: PMATZTZNYRCHOR-IMVLJIQENA-N
• PubChem CID: 132274082
• SMILES: CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C

• Type: Cyclosporin A
• Melting Point: 146.0°C to 151.0°C
• Infrared Spectrum: Authentic
• Loss on Drying: 2% max. (60°C, 3 hrs, 5 mm Hg)
• IUPAC Name: 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
• Formula Weight: 1202.61
• Percent Purity: 98%
• Quantity: 1 g
• Chemical Name or Material: Cyclosporin A

Safety and Handling

Product Identifier

• Cyclosporin A

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Carcinogenicity Category 1B
• Reproductive toxicity Category 1B

Hazard Statement

• H302-Harmful if swallowed.
• H350-May cause cancer.
• H360FD-May damage fertility. May damage the unborn child.

Precautionary Statement

• P201-Obtain special instructions before use.
• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : Cyclosporin A

RUO – Research Use Only