Cytochalasin B, Thermo Scientific Chemicals

Description

An actin-disrupting agent

Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

Solubility
Freely soluble in DMF, DMSO or ethanol at room temperature

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 14930-96-2
• Molecular Formula: C29H37NO5
• Molecular Weight (g/mol): 479.62
• MDL Number: MFCD00077704
• InChI Key: GBOGMAARMMDZGR-UHFFFAOYNA-N
• Synonym: cytochalasin b, cytochalasin b from helminthosporium dematioideum
• PubChem CID: 44634701
• IUPAC Name: 16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H,8H,9H,10H,12aH,13H,14H,15H,15aH,16H,17H,18H-oxacyclotetradeca[3,2-e]isoindole-2,18-dione
• SMILES: CC1C2C(CC3=CC=CC=C3)NC(=O)C22OC(=O)C=CC(O)CCCC(C)CC=CC2C(O)C1=C

• Melting Point: 218°C to 221°C
• Color: White
• Odor: Odorless
• Quantity: 5 mg
• UN Number: UN1544
• Beilstein: 1096207
• Merck Index: 14,2790
• Solubility Information: Freely soluble in DMF, DMSO or ethanol at room temperature
• Formula Weight: 479.61
• Physical Form: Powder
• Chemical Name or Material: Cytochalasin B

Safety and Handling

Product Identifier

• Cytochalasin B

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 1
• Acute toxicity Category 2
• Reproductive toxicity Category 2

Hazard Statement

• H300-Fatal if swallowed.
• H310-Fatal in contact with skin.
• H330-Fatal if inhaled.
• H361-Suspected of damaging fertility or the unborn child.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Cytochalasin B

RUO – Research Use Only