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Tocris Bioscience™ des-His1-[Glu9)-Glucagon (1-29) amide

Glucagon receptor antagonist

Brand:  Tocris Bioscience™ 2216/1

Product Code. 18004092

  • £316.00 / 1mg

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Description

Description

des-His1-[Glu9]-Glucagon (1-29) amide is a glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitro. Blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats.
Specifications

Specifications

95%
des-His1-[Glu9)-Glucagon (1-29) amide
des-His1-[Glu9]-Glucagon (1-29) amide
Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2
Store at -20°C
3358.68
1 mg
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